WEEK+15+MOD,+musculoskeletal

4. Discuss the following terms: -infection -bacteremia -systemic inflammatory response syndrome (SIRS) -sepsis -severe sepsis -septic shock -multiple organ dysfunction syndrome

5. Examine the incidence of severe sepsis and selective risk factors associated with nosocomial sepsis.

6. Discuss the components of pathophysiology related to the client with altered health and progressive degeneration with severe sepsis.

7. Describe the role of inflammatory mediators associated with SIRS and MODS.

8. Analyze the effect of the inflammatory mediators on the client’s cells, tissues and other body systems.

9. Identify the sequence of events in clients with severe sepsis and progressive degeneration.

10. Analyze the clinical manifestations associated with systemic inflammatory response syndrome and multiple organ dysfunction syndrome specific to the following systems: -cardiovascular -respiratory -renal -hematologic -central nervous system -gastrointestinal/hepatic

11. Describe the collaborative management for multiple organ dysfunction syndrome.

12. Examine the etiology and prevention of spinal cord injury.

13. Describe the pathophysiology of the 4 mechanisms of primary injury of the spinal cord. a. Flexion injury b. Hyperextension injury c. Flexion-rotation injury d. Compression injury

14. Examine incomplete and complete lesions, which occur with spinal cord injury.

15. Differentiate between Central Cord Syndrome, Anterior Cord Syndrome, Brown-Sequard Syndrome, and Posterior Cord Syndrome, with respect to their anatomic location and associated clinical manifestations.

16. Explain the cascade of metabolic and cellular events that lead to spinal cord ischemia and hypoxia, responsible for further (secondary) injury.

17. Compare and contrast cervical, thoracic and lumbosacral injuries, in relation to the following systems: respiratory, cardiovascular (include peripheral vascular), urinary, GI, integumentary, metabolic and thermoregulation.

18. Describe the process of events of bone healing following a fracture.

19. Discuss the process of bone remodeling and bone repair.

20. Examine the neurovascular assessment of an extremity following a fracture.

21. Examine the potential complications associated with a fracture and the healing of the fracture.

22. Describe the congenital defect of the skeletal system: developmental dysplasia of the hip.

23. Describe the structure and function of articular cartilage in synovial joints.

24. Compare and contrast the sequence of events leading to joint destruction in osteoarthritis and rheumatoid arthritis.

25. Differentiate between noninflammatory joint disease (Osteoarthritis) and inflammatory joint disease (rheumatoid arthritis) relative their pathophysiology, clinical manifestations, and collaborative management.